The Sera-Mag range of magnetic microparticles are based on patented 1mm magnetic carboxylate modified base particles manufactured by a core-shell process. The surface has a unique cauliflower-like structure with a high carboxylic acid content ensuring a high binding capacity and fast reaction kinetics. Sera-Mag microparticles are colloidally stable in the absence of a magnetic field, however when a magnetic force is applied the particles are separated rapidly and completely from suspensions.

 

Unique Properties	Stable in
Non-specific binding of proteins and other substances Non-leaching, encapsulated magnetite Covalently bound ligands do not leach Surfactant-free - no washing required High surface area per unit mass High ligand binding capacity Low settling rate Size distribution < 10% CV resulting in simultaneous magnetic separation excellent lot-to-lot reproducibility	pH 4 - 12 guanidinium thiocyanate DMF & DMSO to 30% Sonication environments PCR temperature cycling

Sera-Mag Products

• MG-CM Carboxylate-Modified Microparticles
  The 1 mm Sera-Mag MG-CM microparticle surface has a high carboxylic acid content allowing simple covalent coupling of proteins, nucleic acids, etc using standard coupling technology. Standard packaging is 15 mL, 100 mL and 1000 mL at 5% solids. These particles are ideal for colormetric assays, heterogeneous assays, chemiluminescent assays and binding ligands of your choice.
    

• MG-SA Streptavidin-Coated microparticles
  These 1 mm particles contain covalently bound streptavidin and are available in 5 levels of biotin binding capacity ranging from 1000 to 5500 pmol/mg. The covalently bound streptavidin does not leach in aqueous buffers. Standard packaging is 1 mL, 5 mL, 15 mL, 100 mL and 1000 mL at 1% solids. These particles are ideal for molecular biology applications, sample preparation, biotinylated ligand capture and chemiluminescent assays.
    

• MG-OL Magnetic oligo (dT)
  These 1 mm particles contain covalently bound oligo (dT) sequences and posses a high mRNA binding capacity (~6 mg mRNA per mg of MG-OL depending on sample and message length). MG-OL particles have a excellent binding stability of at least 2 years. Standard packaging is 1 mL, 5 mL, 15 mL, 100 mL and 1000 mL at 1% solids. These particles are ideal for RT-PCR, cDNA library construction, subtractive hybridization and affinity purification.
    

For in vitro use only